A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show decreases in opioid outcomes after medical marijuana laws existed among people reporting cannabis use.

According to a new study, ketamine use has risen significantly since 2015. The results highlight the need for closer monitoring of recreational ketamine use.

A study of nearly 10,000 adolescents has identified distinct differences in the brain structures of those who used substances before age 15 compared to those who did not. Many of these structural brain differences appeared to exist in childhood before any substance use, suggesting they may play a role in the risk of substance use initiation later in life, in tandem with genetic, environmental, and other neurological factors.

Teens who think their parents use cannabis are more likely to hold favorable attitudes toward the drug and to consider trying it themselves, according to a new study. The research also reveals that parental monitoring and the closeness of parent-child relationships play crucial roles in adolescents' views about cannabis, often with distinct effects based on the parent's gender.

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to a new study. Endocannabinoids bind to cannabinoid receptors throughout the body that regulate activities, such as learning and memory, emotions, sleep, immune response and appetite.

Evidence has been growing to suggest that tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, poses risks to the developing fetus by impacting brain development. Now a new preclinical research study finds that this could increase the risk of addiction to opioids later in life.

Research shows that a non-hallucinogenic marijuana constituent increases both REM and non-REM sleep in rats. Human trials are now under way.

Men and adolescent boys are increasingly at risk of resorting to the dangerous use of anabolic steroids in a bid to achieve the desired muscular build modeled on social media, warn body image experts. A new review that focused specifically on men found that exposure to social media posts depicting ideal muscular male bodies is directly linked to a negative body image and greater odds of resorting to anabolic-androgenic steroid use.

A new study, using responses from the U.S. National Survey on Drug Use and Health, has found that about 6 percent of pregnant women reported using marijuana during the last month, and many did not associate it with health risks.

As cannabis is legalized and is more accessible in various forms across the country, there is increasing concern among health care providers about potential impact on children. Researchers have new findings to add to the existing evidence that cannabis exposure before birth can negatively impact children.

A new paper explains why there needs to be a shift in cannabis policies to a public health approach as opposed to the prevailing, more punitive approach that pushes abstinence instead of public education. With cannabis now legal to some extent in most U.S. states, the authors say the case for such a shift is all the more urgent.

A collaborative study sheds light on how cannabis use affects brain development in young people, the main one being atrophy of certain regions of the cerebral cortex.

Expanded treatment options, increased naloxone distribution and targeted education campaigns likely led to a 37% reduction in overdose deaths from opioids combined with stimulant drugs other than cocaine, according to the results of a large federally funded study.

A new study suggests that the use of high potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use.