Expanded treatment options, increased naloxone distribution and targeted education campaigns likely led to a 37% reduction in overdose deaths from opioids combined with stimulant drugs other than cocaine, according to the results of a large federally funded study.

A new study suggests that the use of high potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use.

A study reveals a gap between patient and physician attitudes on medical marijuana policies.

Researchers show that a pill form of the drug dronabinol, an FDA-approved synthetic version of marijuana's main ingredient, THC, reduces agitation in patients with Alzheimer's by an average of 30%.

The effects of sustained drug abuse can manifest in many ways. Loss of memory and reduced cognitive functions are some of the effects that can persist for years. Scientists have now identified a mechanism in the brain that generates drug-induced cognitive impairments.

A team of researchers has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of cocaine by moderating the brain's reward response, offering a new therapeutic target for treating addiction.

A new study that details trends among psychiatric hospitalizations between 2015-2019 finds that while most hospitalizations did not involve any substances, methamphetamine-related hospitalizations have increased while overall number of psychiatric hospitalizations remained stable.

Adolescents were more likely to have consumed alcohol or tried marijuana by age 15 if they had later bedtimes and slept fewer hours during the night during childhood and adolescence, according to a new study.

A new study suggests that cannabis, the most commonly used illicit substance worldwide, is associated with an increased occurrence of head and neck cancer.

Cocaine binds to a specific transporter in the brain that is responsible for regulating dopamine levels. Researchers have studied and described the process, producing new knowledge that may bring us a step closer to designing a drug for cocaine abuse.

A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinical trial without the intoxication typically associated with whole plant cannabis. It may even have some memory enhancing effects, according to a new study. For the study, researchers conducted the first human clinical trial investigating the acute effects of CBG on anxiety, stress and mood. The research revealed that 20 mg of hemp-derived CBG significantly reduced feelings of anxiety at 20, 45 and 60 minutes after ingestion compared to a placebo.

Since 2009, U.S. high school seniors have reported steep declines in medical use, misuse and availability of the three most commonly prescribed and misused controlled substances for teens, a new study found.

Researchers have found a significant increase in cannabis use among adults with diabetes in the United States, raising concerns about the potential impact on their health outcomes.

Researchers outline some of the intermediate biological steps that could play into how prenatal cannabis exposure leads to behavioral issues down the line.