Drug Facts in Media

Clinical trial shows promising results in a two-drug combination that curbs methamphetamine use

Mon, 2024-06-10 12:02
A clinical trial on a two-drug therapy for methamphetamine use disorder reduced use of the highly addictive drug for up to 12 weeks after initiation of treatment. Participants in the ADAPT-2 clinical trial who received a combination of injectable naltrexone plus extended-release oral bupropion (NTX+BUPN) had a 27% increase in methamphetamine-negative urine tests, indicating reduced usage. By contrast, the placebo group had an 11% increase in negative tests. To date there is no FDA-approved medication for it.
Categories: Drug Facts

Cannabis use common among patients, with most using it to manage a symptom or health condition

Wed, 2024-06-05 14:23
Nearly one in six patients in primary care reported cannabis use, with 35% of those using at levels indicating moderate- to high-risk use disorder. The findings indicate the need for routine cannabis use screening. Currently few healthcare systems offer this screening in primary care settings.
Categories: Drug Facts

Tiny worm helps uncover long-lasting prenatal effects from amphetamines

Thu, 2024-05-30 16:22
During pregnancy, the effects of therapeutical doses of amphetamine have been investigated on birth outcomes in humans. However, a thorough investigation of the mechanisms underlying the long-term effects of embryonal exposure to addictive doses of amphetamine remains largely unexplored. Using a tiny worm, researchers have revealed the underlying mechanisms of embryonal exposure to methamphetamine (Meth) and amphetamines, a psychostimulant used to treat a variety of brain dysfunctions.
Categories: Drug Facts

New study highlights significant increases in cannabis use in United States

Wed, 2024-05-22 11:03
A new study assessed cannabis use in the United States between 1979 and 2022, finding that a growing share of cannabis consumers report daily or near-daily use and that their numbers now exceed those of daily and near-daily alcohol drinkers. The study concludes that long-term trends in cannabis use parallel corresponding changes in policy over the same period.
Categories: Drug Facts

THC lingers in breastmilk with no clear peak point

Wed, 2024-05-08 07:37
When breastfeeding mothers in a recent study used cannabis, its psychoactive component THC showed up in the milk they produced. The research also found that, unlike alcohol, when THC was detected in milk there was no consistent time when its concentration peaked and started to decline. Importantly, the researchers discovered that the amount of THC they detected in milk was low -- they estimated that infants received an average of 0.07 mg of THC per day. For comparison, a common low-dose edible contains 2 mg of THC. The research team stressed that it is unknown whether this amount has any impact on the infant.
Categories: Drug Facts

New study finds increase in exposures to synthetic tetrahydrocannabinols among young children, teens, and adults

Tue, 2024-05-07 12:59
A sharp rise in exposures to synthetic cannabis products among youth -- some leading to hospitalization -- highlights the need for increased education around the dangers of exposure and increased focus on safe storage and packaging.
Categories: Drug Facts

Follow-up 50 years on finds landmark steroid study remains safe

Mon, 2024-04-22 19:25
A follow-up analysis 50 years later finds no adverse heart health risk from Professor Mont Liggins' landmark steroid study to reduce illness and death for pre-term babies.
Categories: Drug Facts

A common pathway in the brain that enables addictive drugs to hijack natural reward processing

Thu, 2024-04-18 14:51
Researchers have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.
Categories: Drug Facts

Crackdown on illicit drugs detects rise in 'designer' drug substitutes

Mon, 2024-03-25 20:02
As authorities crack down on illicit drugs, experts have issued an alert on the use of the synthetic stimulant pentylone, as new research finds a 75% increase in detections across Australia.
Categories: Drug Facts

Steroid drugs used for HRT can combat E. coli and MRSA

Wed, 2024-03-13 11:55
Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Categories: Drug Facts

Delta-8-THC use reported by 11% of 12th graders in 2023

Tue, 2024-03-12 11:37
Approximately 11% of 12th-grade students across the United States reported past-year use of delta-8- tetrahydrocannabinol (delta-8-THC, or delta-8 for short), according to an analysis of data from the 2023 Monitoring the Future survey. Delta-8 is a psychoactive substance that is typically derived from hemp, a variety of the Cannabis sativa plant. Delta-8 has intoxicating effects similar to delta-9-THC (delta-9), the primary THC component responsible for the 'high' people may experience from using cannabis.
Categories: Drug Facts

'Study drugs' set the stage for other drug use and mental health decline

Mon, 2024-03-11 12:57
Taking 'study drugs' like Adderall without a diagnosis is not only dangerous in itself, but can lead to other drug use and a decline in mental health, according to new research.
Categories: Drug Facts

Continued cocaine use disrupts communication between major brain networks

Wed, 2024-02-28 13:47
New research provides new insights into the brain processes underlying cocaine addiction. The findings are crucial for developing new therapeutics and identifying an imaging marker for cocaine use disorders.
Categories: Drug Facts

Cannabis use linked to increase in heart attack and stroke risk

Wed, 2024-02-28 09:53
More frequent use of cannabis was associated with higher odds of adverse cardiovascular outcomes, finds new study.
Categories: Drug Facts

CBD shown to ease anxiety without the risks that can come with THC

Tue, 2024-02-27 15:21
A new study of 300 people with anxiety shows that the nonintoxicating compound, CBD, found in cannabis can quell anxiety better than THC-dominant products -- and without the side-effects.
Categories: Drug Facts
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